Journal of Prosthodontics News  

Prosthodontic Rehabilitation of a Patient with Hypophosphatasia Using Dental Implants


Now online in the Journal of Prosthodontics, a case report on the prosthodontic rehabilitation of a 24-year-old patient diagnosed with hypophosphatasia (HPP) at age 5.

HPP is an inherited metabolic disorder characterized by low activity of alkaline phosphatases (ALP) reducing the deposition of calcium and phosphorus in hard tissues. Ondonto-HPP is a mild form of the disease that can cause premature exfoliation of teeth.

Once diagnosed, early involvement by a dentist and rational dental treatment planning in a multidisciplinary approach should be organized as a result of the complexity and unpredictably of the disease.

The patient presented for implant treatment because her previous removable partial denture lacked retention and masticatory function was unsatisfactory. The report demonstrates that the exfoliation of permanent teeth can be treated by dental implant-supported fixed restorations in HPP cases.

Currently, all implants have been present for more than 7 years.

Yang Y, Liu Z, Wei L, et al. Prosthodontic rehabilitation of a patient with hypophosphatasia using dental implants: a case report with seven years follow-up. J Prosthodont 2021; https://doi.org/10.1111/jopr.13419


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